JCRB1049 OVMIU
細胞情報
Important Notice(s)Problem of JCRB1047 OVSAYO、JCRB1049 OVMIU、JCRB1050 OVMIU-II
細胞種類：一般細胞 (細胞分譲手数料はこちら)
| 細胞番号(JCRB) | JCRB1049 | 細胞名 | OVMIU |
|---|---|---|---|
| 生物種(日本語) | ヒト | 組織名(日本語) | 卵巣 |
| コメント(日本語) | 腺がん, (OVMIU-IIとは異なるDNAプロファイルを示し、クロスコンタミの疑いあり) | プロフィール | Human cell line derived from ovarian tumour. |
| 別名 | 動物名 | human | |
| 系統名 | 学名・属名 | Homo | |
| 種名 | sapiens | 性別 | F |
| 年齢・月齢 | 46 | 細胞識別情報 | available |
| （癌）原発組織名 | ovary | 病歴情報 | ovarian carcinoma, stage IIIc, not treated before. |
| 転移の有無（Y/N） | No | （癌）転移組織名 | |
| 遺伝的性質 | ER(-) / tumor markers, CA125, CA19-9, TAP, SLX, LDH, ALP E2, E1, DHEA. | 細胞寿命 | infinite |
| ｸﾗｲｼｽＰＤＬ | 形態 | epithelial-like | |
| 一般性状 | Cells are not transplantable to mouse. | 細胞分類 | tumour |
| 細胞樹立者名 | Gorai,I. et.al. | 細胞寄託者 | Gorai,I. |
| 分譲時制限 | コメント | The STR pattern of the OVMIU was consistent with the OVSAYO while the OVMIU-II was expected to be same with the OVMIU. | |
| 入手年 | 2002 | 培養培地 | RPMI1640 medium with 10% fetal bovine serum. |
| 継代方法 | Cells are harvested after treatment with 0.05% trypsin. Change medium every 3-4 days. | 継代時細胞数 | 5 x 10^4 cells/ml |
| 人種 | Japanese | 炭酸ガス濃度 | 5 % |
| 採取組織名 | ovary | 組織型 | adeno carcinoma |
| ウイルスDNA・RNA検出検査 (Detection of virus genome fragment by Real-time PCR) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ウイルスDNA 検出検査 |
tested | ウイルスRNA 検出検査 |
tested | ||||||
| CMV | - | parvoB19 | - | HCV | - | HTLV-1 | - | ||
| EBV | - | HBV | - | HIV-1 | - | HTLV-2 | - | ||
| HHV6 | - | HTLV-1 | - | HIV-2 | - | HAV | - | ||
| HHV7 | - | HTLV-2 | - |
-/negative. +/positive. nt/not tested. (positive (+) does not immediately mean the production of infectious viral particles.) |
|||||
| BKV | - | HIV-1 | - | ||||||
| JCV | - | HIV-2 | - | ||||||
| ADV | - | HPV18 | - | ||||||
| Notes | |||||||||
| Reference | |
|---|---|
| Pubmed id:11121861 | Cyclophosphamide and 5-fluorouracil act synergistically in ovarian clear cell adenocarcinoma cells. Ohta I,Gorai I,Miyamoto Y,Yang J,Zheng JH,Kawata N,Hirahara F,Shirotake S Cancer Lett. 2001 Jan 10;162(1):39-48 |
| Pubmed id:9328139 | Complexity of expression of the intermediate filaments of six new human ovarian carcinoma cell lines: new expression of cytokeratin 20. Yanagibashi T,Gorai I,Nakazawa T,Miyagi E,Hirahara F,Kitamura H,Minaguchi H Br J Cancer. 1997;76(7):829-35 |
| Pubmed id:7535723 | Establishment and characterization of two human ovarian clear cell adenocarcinoma lines from metastatic lesions with different properties. Gorai I,Nakazawa T,Miyagi E,Hirahara F,Nagashima Y,Minaguchi H Gynecol Oncol. 1995 Apr;57(1):33-46 |
| Pubmed id:7882618 | Marked induction of gelatinases, especially type B, in host fibroblasts by human ovarian cancer cells in athymic mice. Miyagi E,Yasumitsu H,Hirahara F,Nagashima Y,Minaguchi H,Miyazaki K,Umeda M Clin Exp Metastasis. 1995 Mar;13(2):89-96 |
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